Associate Scientist

We are seeking an experienced scientist with deep, hands-on expertise in histology and antibody validation to join a fast-paced and highly collaborative scientific environment. This role will support multiple ongoing spatial omics projects including biomarker discovery and target validation initiatives requiring someone who is highly adaptable, detail-oriented, and comfortable balancing planned work with urgent, short-term requests. The ideal candidate thrives in a dynamic environment, approaches shifting priorities as an opportunity, and can deliver high-quality work across a broad range of histology and multiplex imaging workflows.

Responsibilities

• Contribute to and help shape DAGS multiomics and spatial biology experimental strategies.
• Support the maintenance, troubleshooting, and optimization of histology instruments and associated laboratory workflows. Maintain, calibrate, and document the use of laboratory equipment in compliance with internal standards.
• Perform routine and advanced preparation of histological slides from FFPE blocks, including embedding, sectioning, staining, labeling, and quality assessment.
• Perform antibody validation using chromogenic and multiplex immunofluorescence approaches to support assay development and target validation.
• Design, optimize, and validate multiplex immunofluorescence panels using the Lunaphore COMET platform and execute assigned projects with accuracy and timeliness.
• Collaborate with cross-functional and cross-departmental teams to support target evaluation, assay troubleshooting, and technology implementation.
• Manage multiple priorities effectively in a fast-paced setting while maintaining scientific rigor and attention to detail.
• Contribute ideas for workflow improvements, assay optimization, and adoption of novel technologies.

Education

• Ph.D, M.Sc., B.S in a relevant scientific discipline with significant hands-on experience in histological techniques.

Experience

• Demonstrated expertise in antibody validation using chromogenic and multiplex immunofluorescence staining methods.
• Familiarity with automated staining platforms, preferably the Leica BOND system.
• Strong experience in high-plex spatial biology and multiplex immunofluorescence methodologies, including platforms such as Lunaphore COMET, CODEX, CellScape, and imaging mass cytometry.
• Experience operating microscopy systems and modern slide scanners such as Leica GT450, Akoya PhenoImager, or Zeiss Axioscan.
• Proficiency with image visualization and analysis software, such as HALO, QuPath, and ImageJ.
• Strong scientific judgment, critical thinking, and problem-solving skills.
• Excellent communication and collaboration skills, with the ability to work effectively across teams.
• Curiosity, adaptability, and a proactive mindset toward learning and implementing new technologies.

Additional Information

• Preferred Qualifications: * Experience with assay development, optimization, and troubleshooting in a research or translational setting.
• Familiarity with tissue biomarker evaluation, spatial tissue profiling, or pathology-adjacent workflows.
• Experience documenting and standardizing workflows, SOPs, and QC procedures.
• Ability to independently prioritize requests and manage multiple concurrent projects.
• Demonstrated experience working in a matrixed, interdisciplinary environment.
• Exposure to data interpretation and presentation of histology or imaging-based results to scientific stakeholders.